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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.65633196 |
| Normalized Enrichment Score (NES) | -2.110812 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0023973435 |
| FWER p-Value | 0.0050 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HRAS | 1422407_s_at 1424132_at | 938 | 3.277 | 0.0002 | No | ||
| 2 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 5518 | 1.047 | -0.1952 | No | ||
| 3 | MATK | 1421739_a_at 1432329_a_at | 6156 | 0.963 | -0.2116 | No | ||
| 4 | GRB10 | 1425457_a_at 1425458_a_at 1430164_a_at 1440935_at 1441620_at 1446921_at | 6158 | 0.963 | -0.1990 | No | ||
| 5 | RPS6KB1 | 1428849_at 1446376_at 1454956_at 1457562_at 1459951_at 1460705_at | 6539 | 0.907 | -0.2045 | No | ||
| 6 | BAD | 1416582_a_at 1416583_at | 8047 | 0.703 | -0.2641 | No | ||
| 7 | EPOR | 1423344_at | 8134 | 0.690 | -0.2589 | No | ||
| 8 | SNAI2 | 1418673_at 1447643_x_at | 10015 | 0.468 | -0.3387 | No | ||
| 9 | PTEN | 1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at | 10105 | 0.457 | -0.3367 | No | ||
| 10 | STAT3 | 1424272_at 1426587_a_at 1459961_a_at 1460700_at | 10629 | 0.405 | -0.3553 | No | ||
| 11 | DOK1 | 1417790_at | 10940 | 0.367 | -0.3646 | No | ||
| 12 | SPRED1 | 1423160_at 1423161_s_at 1423162_s_at 1428777_at 1441517_at 1442859_at 1443652_x_at 1445228_at 1452911_at 1460116_s_at | 11703 | 0.284 | -0.3957 | No | ||
| 13 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 12122 | 0.239 | -0.4117 | No | ||
| 14 | PTPN11 | 1421196_at 1427699_a_at 1451225_at | 12606 | 0.188 | -0.4313 | No | ||
| 15 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 13226 | 0.116 | -0.4580 | No | ||
| 16 | SPRED2 | 1423001_at 1434403_at 1436892_at 1441415_at 1441802_at | 13306 | 0.105 | -0.4603 | No | ||
| 17 | JAK2 | 1421065_at 1421066_at | 13318 | 0.103 | -0.4594 | No | ||
| 18 | CBL | 1434829_at 1446608_at 1450457_at 1455886_at | 13354 | 0.098 | -0.4597 | No | ||
| 19 | KITLG | 1415854_at 1415855_at 1426152_a_at 1440621_at 1448117_at | 13663 | 0.058 | -0.4730 | No | ||
| 20 | PTPRO | 1417676_a_at 1425863_a_at 1457771_at | 14830 | -0.110 | -0.5248 | No | ||
| 21 | SHC1 | 1422853_at 1422854_at | 14924 | -0.125 | -0.5274 | No | ||
| 22 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 14972 | -0.133 | -0.5278 | No | ||
| 23 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 15248 | -0.177 | -0.5381 | No | ||
| 24 | KIT | 1415900_a_at 1452514_a_at 1459588_at | 16700 | -0.498 | -0.5978 | No | ||
| 25 | GAB1 | 1417693_a_at 1417694_at 1448814_at | 16873 | -0.552 | -0.5984 | No | ||
| 26 | MAP2K1 | 1416351_at | 16935 | -0.572 | -0.5937 | No | ||
| 27 | RAF1 | 1416078_s_at 1425419_a_at | 17235 | -0.675 | -0.5985 | No | ||
| 28 | GRB2 | 1418508_a_at 1449111_a_at | 17468 | -0.764 | -0.5990 | No | ||
| 29 | MITF | 1422025_at 1455214_at | 17602 | -0.821 | -0.5943 | No | ||
| 30 | SH2B3 | 1433455_at 1442756_at 1450183_a_at | 17798 | -0.902 | -0.5914 | No | ||
| 31 | SOS1 | 1421884_at 1421885_at 1421886_at | 18731 | -1.279 | -0.6172 | No | ||
| 32 | MAPK3 | 1427060_at | 19380 | -1.691 | -0.6245 | Yes | ||
| 33 | STAT5A | 1421469_a_at 1450259_a_at | 19892 | -2.079 | -0.6206 | Yes | ||
| 34 | GRAP2 | 1456432_at | 20676 | -2.983 | -0.6172 | Yes | ||
| 35 | PTPN6 | 1456694_x_at 1460188_at | 20681 | -2.991 | -0.5781 | Yes | ||
| 36 | CRKL | 1421953_at 1421954_at 1425604_at 1436950_at | 20897 | -3.384 | -0.5434 | Yes | ||
| 37 | VAV1 | 1422932_a_at | 21119 | -3.839 | -0.5031 | Yes | ||
| 38 | PDPK1 | 1415729_at 1416501_at 1459775_at 1459776_x_at | 21147 | -3.899 | -0.4531 | Yes | ||
| 39 | CREBBP | 1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at | 21224 | -4.102 | -0.4027 | Yes | ||
| 40 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 21309 | -4.363 | -0.3492 | Yes | ||
| 41 | SOCS1 | 1440047_at 1450446_a_at | 21625 | -5.963 | -0.2853 | Yes | ||
| 42 | STAT1 | 1420915_at 1440481_at 1450033_a_at 1450034_at | 21734 | -6.804 | -0.2009 | Yes | ||
| 43 | GSK3B | 1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at | 21861 | -7.833 | -0.1037 | Yes | ||
| 44 | TEC | 1441524_at 1460204_at | 21906 | -8.156 | 0.0014 | Yes |
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